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It is the most common serious heart rhythm abnormality in people over the age of 65.

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On 6 April 1999, the Company changed its name to AstraZeneca PLC. For the majority of people who have one, a PFO is of no health consequence, even though blood continues to leak from the right atrium to the left, according to the American Heart Association. The difference was staggering.

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In his words, there was too much to be done. Bristol-Myers Squibb will lose protection on Plavix, http://takatsuna.com/ a drug used to prevent heart attacks and strokes; GlaxoSmithKline () will lose asthma treatment Advair; and Eli Lilly () will relinquish protection on its drug to treat schizophrenia, Zyprexia.

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